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Publications

Recent publications: original articles

Tang-Huau TL, Gueguen P, Goudot C, Durand M, Bohec M, Baulande S, Pasquier B, Amigorena S, Segura E (2018). Human in vivo-generated monocyte-derived dendritic cells and macrophages cross-present antigens through a vacuolar pathway. Nature Communications 9, 2570. 10.1038/s41467-018-04985-0
https://doi.org/10.1038/s41467-018-04985-0

Goudot C, Coillard A, Villani AC, Gueguen P, Cros A, Sarkizova S, Tang-Huau TL, Bohec M, Baulande S, Hacohen N, Amigorena S, Segura E (2017). Aryl hydrocarbon receptor controls monocyte differentiation into dendritic cells versus macrophages. Immunity. 47(3):582-596.
https://doi.org/10.1016/j.immuni.2017.08.016

Segura E, Touzot M, Bohineust A, Cappuccio A, Chiocchia G, Hosmalin A, Dalod M, Soumelis V, Amigorena A (2013). Human inflammatory dendritic cells induce Th17 differentiation. Immunity 38(2):336-48.
https://doi.org/10.1016/j.immuni.2012.10.018

Segura E, Durand M, Amigorena S (2013) Similar antigen cross-presentation capacity and phagocytic functions in all freshly isolated human lymphoid organ-resident dendritic cells. J Exp Med 210(5):1035-47.
https://doi.org/10.1084/jem.20121103

Segura E, Valladeau-Guilemond J, Donnadieu M-H, Sastre-Garau X, Soumelis V, Amigorena S. (2012). Characterisation of resident and migratory dendritic cells in human lymph nodes. J Exp Med. 209(4): 653.
https://doi.org/10.1084/jem.20111457

Recent publications: review articles

Tang-Huau TL and Segura E (2018). Human in vivo-differentiated monocyte-derived dendritic cells. Semin Cell Dev Biol.S1084-9521(17)30362-2.
https://doi.org/10.1016/j.semcdb.2018.02.018

Durand M and Segura E (2015). The known unknowns of the human dendritic cell network. Front. Immunol. 6:129.
https://doi.org/10.3389/fimmu.2015.00129

Segura E and Amigorena S (2015). Cross-presentation in mouse and human dendritic cells. Adv Immunol. 127:1-31.
https://doi.org/10.1016/bs.ai.2015.03.002

Segura E, Amigorena S (2014). Cross-presentation by human dendritic cell subsets. Immunol letters. 158(1-2):73-78.
https://doi.org/10.1016/j.imlet.2013.12.001

Segura E, Amigorena S (2013). Inflammatory dendritic cells in mice and humans. Trends Immunol. 34(9):440-5.
https://doi.org/10.1016/j.it.2013.06.001

Recent publications: opinion articles

Segura E, Soumelis V. (2017) Of Human DC Migrants and Residents. Immunity. 46(3):342-344.
https://doi.org/10.1016/j.immuni.2017.03.006

Guilliams M, Ginhoux F, Jakubzick C, Naik SH, Onai N, Schraml BU, Segura E, Tussiwand R, Yona S (2014). Dendritic cells, monocytes and macrophages: a unified nomenclature based on ontogeny. Nat Rev Immunol. 14(8):571-8.
https://doi.org/10.1038/nri3712

Recent publications: book chapters and protocols

Coillard A and Segura E. (2018). Visualization of RNA at the Single Cell Level by Fluorescent in situ Hybridization Coupled to Flow Cytometry. Bio-protocol 8(12): e2892.
https://doi.org/10.21769/BioProtoc.2892

Segura E. (2016) Review of Mouse and Human Dendritic Cell Subsets. Methods in Molecular Biology Series. 1423:3-15
https://doi.org/10.1007/978-1-4939-3606-9_1

Durand M and Segura E. (2016) Dendritic cell subsets purification from human tonsils and lymph nodes. Methods in Molecular Biology Series. 1423:89-99
https://doi.org/10.1007/978-1-4939-3606-9_6

Segura E. (2016) Cross-presentation assay for human dendritic cells. Methods in Molecular Biology Series. 1423:189-98
https://doi.org/10.1007/978-1-4939-3606-9_14

Vremec D and Segura E. (2013) The Purification of Large Numbers of Antigen Presenting Dendritic Cells from Mouse Spleen. Methods in Molecular Biology Series. 960:327-50
https://doi.org/10.1007/978-1-62703-218-6_24

Recent publications: major collaborations

Michea P, Noël F, Zakine E, Czerwinska U, Sirven P, Abouzid O, Goudot C, Scholer-Dahirel A, Vincent-Salomon A, Reyal F, Amigorena S, Guillot-Delost M, Segura E, Soumelis V. (2018). Adjustment of dendritic cells to the breast-cancer microenvironment is subset specific. Nature Immunology. 19(8):885–897.
https://doi.org/10.1038/s41590-018-0145-8

Cepika AM, Banchereau R, Segura E, Ohouo M, Cantarel B, Goller K, Cantrell V, Ruchaud E, Gatewood E, Nguyen P, Gu J, Anguiano E, Zurawski S, Baisch JM, Punaro M, Baldwin N, Obermoser G, Palucka K, Banchereau J, Amigorena S, Pascual V.(2017) A multidimensional blood stimulation assay reveals immune alterations underlying systemic juvenile idiopathic arthritis. J Exp Med. 214(11):3449-3466.
https://doi.org/10.1084/jem.20170412

De Monte A, Olivieri CV, Vitale S, Bailleux S, Castillo L, Giordanengo V, Maryanski JL, Segura E, Doglio A. (2016) CD1c-Related DCs that Express CD207/Langerin, but Are Distinguishable from Langerhans Cells, Are Consistently Present in Human Tonsils. Front Immunol. 7:197.
https://doi.org/10.3389/fimmu.2016.00197

Desch AN, Gibbings SL, Goyal R, Kolde R, Bednarek J, Bruno T, Slansky JE, Jacobelli J, Mason R, Ito Y, Messier E, Randolph GJ, Prabagar M, Atif SM, Segura E, Xavier RJ, Bratton DL, Janssen WJ, Henson PM, Jakubzick CV.(2016) Flow Cytometric Analysis of Mononuclear Phagocytes in Nondiseased Human Lung and Lung-Draining Lymph Nodes. Am J Respir Crit Care Med. 193(6):614-26.
https://doi.org/10.1164/rccm.201507-1376OC

Mintern JD, Macri C, Chin WJ, Panozza SE, Segura E, Patterson NL, Zeller P, Bourges D, Bedoui S, McMillan PJ, Idris A, Nowell CJ, Brown A, Radford KJ, Johnston AP, Villadangos JA. (2015) Differential use of autophagy by primary dendritic cells specialized in cross-presentation. Autophagy. 11(6):906-17.
https://doi.org/10.1080/15548627.2015.1045178

Reuter A, Panozza SE, Macri C, Dumont C, Li J, Liu H, Segura E, Vega-Ramos J, Gupta N, Caminschi I, Villadangos JA, Johnston AP, Mintern JD. (2015) Criteria for dendritic cell receptor selection for efficient antibody-targeted vaccination. J Immunol. 194(6):2696-705.
https://doi.org/10.4049/jimmunol.1402535